Extended use of raltegravir in the treatment of HIV-1 infection: optimizing therapy
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چکیده
منابع مشابه
Extended use of raltegravir in the treatment of HIV-1 infection: optimizing therapy
Raltegravir is the first licensed compound in 2007 of the new integrase inhibitor drug class. At the dose of 400 mg twice daily, raltegravir showed a potent antiviral action in antiretroviral-naïve patients when associated with tenofovir and emtricitabine. Raltegravir was also found to be highly active in antiretroviral-experienced patients with virological failure and displaying multiresistant...
متن کاملRaltegravir: Its use in the Treatment of HIV Infection
Raltegravir is the fi rst integrase strand transfer inhibitor to be approved for the treatment of HIV infection. Administered orally in doses of 400 mg twice daily, it is well-tolerated and has minimal drug-drug interactions with coadministered antiretrovirals and other agents. In clinical trials including treatment-experienced and treatment-naïve HIV-infected adults, raltegravir in combination...
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چکیده ندارد.
15 صفحه اولRaltegravir with optimized background therapy for resistant HIV-1 infection.
BACKGROUND Raltegravir (MK-0518) is an inhibitor of human immunodeficiency virus type 1 (HIV-1) integrase active against HIV-1 susceptible or resistant to older antiretroviral drugs. METHODS We conducted two identical trials in different geographic regions to evaluate the safety and efficacy of raltegravir, as compared with placebo, in combination with optimized background therapy, in patient...
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abstract nowadays, the science of decision making has been paid to more attention due to the complexity of the problems of suppliers selection. as known, one of the efficient tools in economic and human resources development is the extension of communication networks in developing countries. so, the proper selection of suppliers of tc equipments is of concern very much. in this study, a ...
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ژورنال
عنوان ژورنال: Infection and Drug Resistance
سال: 2010
ISSN: 1178-6973
DOI: 10.2147/idr.s8673